Psychiatry and neurology care transformed.

An AI-enabled paradigm for precision medicine in CNS diseases

Our Mission

Proprietary platform combining stem-cell technology, genomics and AI for treatment optimization and effective drug development in psychiatry and neurology

Genetika+ leverages Nobel-Prize winning technology to generate iPSC-derived neurons from each individual. Robust, consistent, and scalable.

Precision Medicine. Realized.

Each patient’s own derived brain cells inform their optimal treatment

Powered by Computer Vision

AI and computer vision applied on
multi-modality data for unprecedented accuracy

Comprehensive Biobank and Data repository

Encompassing 100's of thousands of datapoint from hundreds of patients in multiple diseases

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our data

Multi-modality data drives evidence-based practice

The largest and most comprehensive databank combining imaging, genomic and clinical data from patients’-derived neurons.

1.5M+

Clinical Data Points

2,500+

Microscopy Features

20,000+

RNA Transcripts/Patients

120,000+

Clinical Patients

Awards & Recognitions

Genetika+ is proud to be recognized by organizations around the world for our impact on the healthcare ecosystem.

who we help

We Transform Depression

Genetika+ is transforming Psychiatry & Neurology care by providing patients, physicians, drug developers and researchers, for the first time, an approach to precision medicine through the lense of each patient’s unique neurobiology, with deep actionable mechanistic insight into disease and patient characteristics.

A smiling doctor with a stethoscope around his neck and a clinic in the background.

For Providers

Genetika+’s evidence-based tests and services offers the quality and commitment you need to help guide treatment strategies for your psychiatry and neurology diseases' patients.

A happy lady wearing a black coat with an office look in the background.

For BioPharma

From initial discovery to launch of a new therapy, we are your ideal partner to help make your next breakthrough the standard of care.

For Patients

We are committed to providing specific cell-based insights into your psychiatric or neurological disorder to help your doctor guide a personalized care plan.

How it works

step 1

Patient Sample

The process starts with a standard patient blood collection. Blood samples can be obtained in any setting including the comfort of an individual’s home.

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A rectangle shaped structure having pillars inside it with a white background

Stem Cell Conversion with white background

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step 2

Stem Cell Conversion

Through a process that induces protein expression of key factors found in early development peripheral blood cells are reprogrammed to pluripotent stem cells using Nobel-Prize winning technology.

step 3

Brain in a Dish

Once created, these stem cells are treated with a sequence of unique growth factors to generate specific neuronal subtypes that reflect the brain region most relevant for disease.

Patient-derived neurons are then exposed to compounds or other challenges and features relevant for neuronal function, activity, and communication are analyzed using state-of-the-art computer vision and deep learning algorithms.

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A cube shaped dotted structure having white background

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step 4

AI Predictions

Powerful AI tools are used to combine the various features into a single score that reflects the compound’s efficacy on the specific patient’s neurons.

This score is then combined with clinical and demographic features of the patient for environmental effects and potential drug adverse effects, as well as with the patient's pharmacokinetic profile, resulting in a combined score for drug responsiveness.

step 5

Deep
Understandings

Using patients' own derived neurons allows for the first time insight into drug efficacy in individual patients, even before first-in-human studies.

Using the combination of imaging and molecular analysis, we obtain a deep understanding of the mechanism of action of each compound, its interaction with clinical and environmental factors, and comparison with existing or in-development drugs.

The outputs are actionable insights from mechanistic underpinnings in individual patients.

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Side view of brain with white background

How it works

step 1

Patient Sample

The process starts with a standard patient blood collection. Blood samples can be obtained in any setting including the comfort of an individual’s home.

step 2

Stem Cell Conversion

Through a process that induces protein expression of key factors found in early embryos, peripheral blood cells are reprogrammed to pluripotent stem cells using Nobel prize winning technology.

step 3

Brain in a Dish

step 4

AI Predictions

Powerful AI tools are used to combine the various features into a single score that reflects the compound’s efficacy on the specific patient’s neurons.

This score is then combined with clinical and demographic features of the patient for environmental effects and potential drug adverse effects, as well as with the patient pharmacokinetic profile, resulting in a combined score for drug responsiveness.

step 5

Deep Understandings

Using patient’s own derived neurons allows for the first time insight into drug efficacy in individual patients, even before first-in-human studies.

Using the combination of imaging and molecular analysis, we obtain deep understanding of the mechanism of action of each compound, its interaction with clinical and environmental factors, and comparison with existing or in-development drugs.

The outputs are actionable insights from mechanistic underpinnings in individual patients.